Tag Archives: CFS

Gluten sensitivity and fibromyalgia… is there really a link?

Marcusby Holistic Osteopath, Marcus Webb

By the time you read this little article I am sure you will have heard about a study linking gluten sensitivity with fibromyalgia and reporting on how ‘remarkable clinical improvement can be achieved with a gluten-free diet in patients with fibromyalgia (FM) even if coeliac disease has been ruled out’. The conclusion also goes on to say that ‘non-coeliac gluten sensitivity may be an underlying treatable cause in FM syndrome’.

However, the plot thickens; in all 20 of the FM subjects studied biopsies of their intestine revealed a pathological change known as intraepithelial lymphocytosis, a finding the authors use to help support their hypothesis that gluten sensitivity is a causal agent and underlies FM. This cause and effect relationship that this latest study hints at does sound convincing especially when we keep in mind that intraepithelial lymphocytosis has been associated with gluten sensitivity in the past but should we be jumping to such a definitive conclusion; what about those FM patients who don’t have intraepithelial lymphocytosis, were they removed from the study because they did not respond to a gluten-free diet? Don’t get me wrong, I am not trying to discredit or down play the study or the potential benefits of a gluten free diet in cases of FM but I am aware that many FM sufferers may read this and feel that they have to follow a gluten-free diet in order to get better but before going on it may be good to lay out a little additional information about intraepithelial lymphocytosis.

Within the tissue of the gut known as (epithelial tissue) special white blood cells known as lymphocytes reside waiting like guard on duty to be triggered into life by an invading army. In the case of the gut this is would normally be a bacterial infection. In around 3% of routine biopsies increased levels of lymphocytes can be observed (ie. intraepithelial lymphocytosis) and between 9-40% of cases celiac disease has eventually been diagnosed. In some cases intraepithelial lymphocytosis occurs in other multi-system disorders such as Hashimoto’s thyroiditis, Graves’s disease, rheumatoid arthritis, psoriasis, multiple sclerosis, Systemic lupus erythematosus, ankylosing spondylitis and autoimmune enteropathy. The other cases tend to be viewed as a non-specific finding related to other health issues such as bacterial overgrowth (SEBO), inflammatory damage secondary to non-steroidal anti-inflammatory drug use or other chronic inflammatory bowel disease. In other words, the presence of intraepithelial lymphocytosis is not diagnostic of gluten sensitivity but in the absence of other causes gluten sensitivity could be a possibility since it has been reported to account for around 10% of the cases of intraepithelial lymphocytosis but it should be kept in mind that hypersensitivity to other non-gluten components of food may also trigger this tissue change. Interestingly, a good number of the 20 subjects had co-existing health problems that have also been linked with the bowel tissue chances characteristic of intraepithelial lymphocytosis such as psoriasis (in 2 cases), hypothyroidism (in 3 cases), inflammarory/irritable bowel (in 5 cases) and gastric reflux (in 10 cases) which is a problem that commonly receives PPI drug therapy. As a drug class, PPI’s are also known to trigger intraepithelial lymphocytosis. However you critique this study as much as you want but what you can’t ignore is the outcome; for many, great relief of their chronic and disabling symptoms using a drug-free approach.

For many FM sufferers having a condition that is resistant to conventional therapies places them in a real corner when it comes to treatment and management options. From my experiences working with FM/CFS sufferers we tend to do what works or what works for that person! Science tends to take its time in catching up with the clinical observations but while it is catching up in many cases there is no real harm in exploring options that appear to have some evidence to support their use such as a trial of a gluten-free diet. From the results of the current study the gluten-free diet was followed for 16 months on average but in one case (a FM sufferer for 20 years) improvement in pain, fatigue and gut symptoms were felt after just 5 months and in another case (a sufferer for 10 years) complete remission of FM and improvements in gut and migraine was also observed after just 5 months. In some cases significant improvements and a return to normal life activities and work were seen after more prolonged (over 30 months) exposure to the gluten-free diet. However you look at it, cutting the gluten has made a dramatic difference to many sufferers in this small study.

If you feel that a gluten free approach is something you fancy trying its not a diet to be taken on lightly… so many foods contain gluten! Despite this, I would advise that you seriously consider going gluten free if your FM is of long standing and you have exhausted all other approaches. Keep in mind that you may have to stick to it for many months before you feel any tangible benefits but again, for what its worth, I can support the observations that many ill-defined inflammatory and pain related conditions simply improve with the elimination of gluten.

To help get you started you should avoid Barley, bulgar wheat, couscous, durum wheat, rye, semolina, spelt, wheat, all biscuits, breads, cakes, chapattis, crackers, muffins, pastries, pizza bases, muesli, wheat based breakfast cereals and anything made from wheat, rye or barley flour. By no stretch of the imagination is this a complete gluten free diet but it’s a start and something you can instigate today. Sitting down with an experienced nutritionist or naturopath should be your next step so you can get a more complete understanding of the complete gluten free diet and what it involves. In the early days of a gluten free diet I tend to recommend the use of a special dietary enzyme supplement based in a blend of plant derived gluten splitting enzymes. In addition to the cellulose digesting enzyme known as cellulase the key ingredient in Gluten Relief is Dipeptidyl Peptidase IV (or DPP-IV for short). DPP-IV is a type of protein splitting enzyme, known as a protease, and has been shown to break down the wheat protein gluten and milk protein casein. This combines with alpha-galactosidase to aid in the digestion of long chain sugars found in beans, broccoli, cabbage, sprouts etc… Using an enzyme preparation such as Gluten Relief (by the Canadian manufacturer Natural Factors) does not replace in anyway a gluten free diet but when you are unsure or are out and about with limited choices it may help to ‘defuse’ a potential gluten containing meal.

Link to study: Fibromyalgia and non-celiac gluten sensitivity: a description with remission of fibromyalgia. 

Link to Gluten Relief product

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Vitamin B12 – the story continues

Marcus Webb

Observations and comments by Marcus Webb

Vitamin B12 has always been associated with fighting fatigue and supporting nerve function. However, this complex vitamin with many biological functions that new research indicates extend beyond simple physical wellbeing.  

Vitamin B12 has an established key role is the normal functioning of the brain and nervous system as well as for the formation of healthy blood cells and is involved in the metabolism of every cell in the body. For such an essential nutrient it may come as a surprise that the human body is unable to produce its own B12 and is completely reliant on dietary sources. While some may quote authorities who state that our bowel bugs generate some vitamin B12 it has been shown that this tiny trickle is not absorbed from the colon and serves as no real nutritional source. We vitamin B12, albeit in small amounts, but we have to get it from our diet. Some key dietary sources are describe later on but in essence there is no reliable non-animal source of vitamin B12 making it very difficult for strict vegetarians or vegans to obtain significant amounts.

Interestingly, vitamin B12 was initially discovered due to its relationship with the condition pernicious anaemia. This is an autoimmune disease whereby the cells in the stomach responsible for secreting intrinsic factor (IF), which is crucial for the absorption of B12, are destroyed.

Taking vitamin B12

Vitamin B12 is often used to treat nerve pain. In most cases, the reported benefit of B12 is related to the injected form of B12 in people suffering from nerve pains in relation to diabetic neuropathy or shingles pain.

There have been some news stories relating to poor B12 absorption in people taking gastric acid blocking drugs. These drugs take effect on the same cells within the stomach that produce IF. In regular users, regular tablets or capsules of B12 will not help much because the absorption of B12 has become impaired as a consequence of the drug action. This is where the suckable/chewable tablets (B12 Infusion tablets from Enzymatic Therapy) come into their own. Vitamin B12 can be effectively absorbed across the delicate membranes of the mouth in sufficient amounts to readdress any deficiency without the need for injection therapy in most cases. For those with true pernicious anaemia who need regular injections of B12 every 3 months a top-up using the B12 Infusion tablets in the month leading up to the next injection can offer a great ‘lift’ for those who notice a general low energy phase before their next injection. So long as the B12 is in the biologically active form known as methylcobalamin and in a chewable/suckable form dosing up on one tablet per day for a month or so could make all the difference to fatigue or ‘brain fog’. Even if you have not been using the acid-blocking drugs, it may be worth trying a course of sublingual B12 for a month especially if you are over 50 years old or follow a strict vegetarian or vegan lifestyle.

Chronic Fatigue Syndrome, Fibromyalgia and Vitamin B12

Scientific studies into the causes of fibromyalgia (FM) and chronic fatigue syndrome (CFS) are always interesting, especially when they appear to support what we notice in the clinic. In the case of vitamin B12 many FM/CFS sufferers report improved energy and overall well-being following a course of high-dose B12 supplementation over 4-6 weeks. Lending some scientific evidence to this anecdotal observation, a study carried out in Sweden back in 1997 gave support to the use of B12 in FM/CFS cases when it was shown that the fluids surrounding the brain and spinal cord (the cerebrospinal fluid of CSF) was significantly lower in vitamin B12 than expected. Having such a low CSF B12 level was closely associated with increased levels of a metabolite known as homocysteine. This in turn was linked to profound symptoms of fatigue. The study concluded that these findings were probably contributing to the FM/CFS in their study group. Sadly, since then, little work has been performed in this area of vitamin B12 research but a team from Kings College did provide preliminary evidence of reduced functional B vitamin status in CFS patients. It’s not often practical to perform routine blood testing for B-vitamin status in cases of FM/CFS let alone sampling of the CSF, but in the holistic management of this complex spectrum of disorders, a trial of vitamin B12 or a good vitamin B complex often yields impressive results and is well worth considering.

Product link: BioActive B12 infusion 1000mcg vitamin B12 in the sublingual methylcobalamin form

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Ribose Increases Energy an Average 61% in CFS and Fibromyalgia

Multicenter Study Shows Ribose Increases Energy an Average 61% in CFS and Fibromyalgia

Summary

Fibromyalgia represents a cellular energy crisis with many causes. Taking steps to increase energy production can often be helpful. One such method is outlined by the “SHINE Protocol” (Sleep, Hormones, Infections, Nutrition, and Exercise) which was shown to be highly effective in an earlier pilot and placebo-controlled study. A new just-published multicenter study of 257 people with CFS/FMS at 53 health clinics showed that d-ribose supplementation increased energy an average of 61% at three weeks, while also improving sleep, cognitive function, pain, and overall well-being. 

Have you been feeling like a zombie lately? You’re not alone! But new research is again showing more reason for hope.

Read the full report here.

Ribose product link here.

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10 top tips for the 21st century syndrome; unexplained fatigue

We all get phases of feeling tired but there is a big difference between occasional tiredness and the incapacitating effects of true fatigue. However, before chronic fatigue syndrome is diagnosed a number of easily fixable health issues can be addressed. Some will need you to work with your doctor while others will simply involve a few basic lifestyle changes.

If you or one of your family is suffering from fatigue work your way through our 10-point check list, you may discover one or more pointers that could make all the difference to your health and boost your natural energy levels again.

  1. Your sleeping, but are you?: If you feel that you are getting enough sleep but are still feeling fatigued and can’t fathom it may be worth considering a condition known as sleep apnoea. This problem causes interrupted breathing during sleep and as a result disturbs your sleep but does not necessarily to a point where you wake up. Because you body and brain need a certain amount of sleep to feel refreshed any disturbance of this delicate balance can result in unexplained fatigue if its not picked up on. In the UK, sleep apnoea affects 4 in 100 middle aged men and around 2 in 100 middle aged women with around 60% of the over 60’s experiencing the problem. One of the quick fixes for sleep apnoea is simply loosing weight especially is you carry fat around your neck.
  2. Could you be anaemic? If you are a women and having regular periods, the monthly blood loss can add up, especially If you are not obtaining enough dietary iron to help replace the losses. A low level of circulating red blood cells can cause profound fatigue because adequate oxygen levels will not reach the tissues of the body. There can be many causes for anaemia so its worth getting a blood test but you can easily top up your iron levels by eating iron-rich foods such as lean red meat, liver and shellfish. In general, vegetarian iron is not as easy to absorb but is available in beans, bran flakes, Tofu, figs, kale and lentils. If you feel you can’t get your iron up through diet alone supplements can help.
  3. One coffee too many? Many of us will reach for a mug of coffee to help fight off fatigue because we all know that coffee can boost alertness. However, the positive effects of this pick-me-up are seen in moderate intake levels but the effects tend to diminish the more we drink. In fact, with higher levels of intake coffee simply causes agitation, raised heart rate and blood pressure and, ironically, fatigue! If you are hitting the coffee more that you feel you should, start cutting back slowly to avoid withdrawals and headaches. Also be aware of the caffeine content of soft drinks. Dropping your coffee intake can actually boost energy!
  4. Check your sugars. It’s not uncommon for diabetes to become an issue the older we get. Type-2 diabetes can creep up on us in a rather stealthy manner and present itself with unexplained fatigue in the early stages. If the dietary sugars stay in the blood and don’t get into the cells we suffer from fatigue. Glucose is a key nutrient needed by the cells to generate energy. Having it circulating in the blood but not getting into the cells causes an energy crisis with fatigue as a prime symptom. A family history may point to Type-2 diabetes but a simple blood test is all that is needed to diagnose it. Adopting a whole food diet and avoiding the cakes and sweeties is a must. Cinnamon or fenugreek supplements can help regulate sugar metabolism and are worth considering.
  5. The wrong or not enough of the right foods. Skipping meals or not eating enough will contribute to an energy crisis within the body. Even at rest, our bodies burn food to keep the metabolic fires burning in each and every cell. Not enough food makes us feel fatigued and can adversely affect our ability to function physically and emotionally. Equally as bad is existing on junk food which tends to be sugar high and nutrient low. Getting your sugar fix will play havoc with your blood chemistry that further contributes to fatigue. Try and eat regularly and make sure that your complex (unrefined) carbohydrates and proteins are at the centre of your meals; poached eggs on whole meal toast is a great start to the day!
  6. The hormone connection. Sitting in the front of our neck is a special gland that is at the heart of regulating our metabolic rate. Known as the thyroid gland, it produces the hormone thyroxin, which, in turn, keeps our metabolic rate on the right tracks. If this gland starts to fail the hormone level drops and our overall metabolic rate shows and we can experience severe fatigue. Getting a blood test will confirm what type of thyroid problem you may have but in some cases very early cases can be overlooked. Borderline low thyroid function may be an issue in those with medically unexplained fatigue. To help determine if this is the case a simple body temperature test can help. Despite being quite controversial the Barns Temperature test may uncover a sub-clinical low thyroid condition.
  7. Check your water works. When we are ill we tend to want to go to bed and sleep it off. To a lesser degree, a background non-acute infection can cause unexplained fatigue. Bladder infections may be a cause of fatigue especially if the infection is not at an acute level but grumbling away as a chronic infection. Testing a sample of urine is easy and can help detect these infections. While antibiotics may be needed by some, using a slow release cranberry and d-mannose supplement can help keep the bladder clear.
  8. Feeling low? While feeling low can be thought of as an emotional issue depression does affect the body on a physical level. Those suffering from depression will commonly complain of fatigue as a key feature of the problem. Because of the complex nature of depression, other factors such as poor appetite and sleep disturbance all add up and compound the feelings of fatigue and tiredness. For those with mild to moderate depression a course of St Johns wort may help lift the mood but care is needed if you are taking other medications. In general, you should seek professional support of you feel depression could be an issue.
  9. Dehydrated? You don’t have to be a sports fanatic to take control of your fluid intake. Your body just sitting at a desk, at a PC or driving a car required adequate hydration for optimal health and performance. Drinking coffee in addition to the comments in point 3, also stimulated the need to have a wee. Coffee is a strong diuretic. However, sipping bottled water is the way to maintain adequate hydration. Even mild dehydration can be associated with fatigue. You can check your hydration level by looking at the colour of your urine; it should be light in colour. Dark urine can be a sign of dehydration and an indication that you need to drink more water.
  10. Are you a shift worker? We all have an internal body clock that tells us when it’s time for bed. Forcing this system to adjust to shift work can cause the body to become confused regarding the sleep-wake cycle so you have trouble sleeping during the day while you find it difficult to concentrate and function when you should really be sleeping. Although we can manage for a while, prolonged exposure to this can be a cause of fatigue. To help ease the effects of shift work try to limit your exposure to daylight after a night shift and make your bedroom as dark and as quiet as possible.

Useful resources:

Dr Jacob Teitelbaum MD., expert on chronic fatigue syndrome

Health supplements recommended by Dr Teitelbaum

 

 

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XMRV virus & CFS/ME: it’s 15 minutes of fame looks to be up!

Following up on our previous posts regarding the discovery of a virus known as XMRV may lie at the heart of many cases of CFS/ME new research looks to blow this idea out of the water! According to the journal Nature, “XMRV’s 15 minutes of fame seem to be up“.
At a recent workshop on CFS/ME, John Coffin, a retrovirologist at Tufts University in Boston whose team showed that XMRV is a laboratory hybrid unlikely to cause a natural human infection. However, a single infectious agent, such as XMRV, is unlikely to explain the condition, but some patients seem to develop the condition not long after being infected with agents such as Epstein–Barr virus.
In Britain, the MRC is accepting research proposals for a new programme devoted exclusively to CFS. The goal of the programme is to draw top-notch scientists into the field.
In the mean time… watch this space!

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Ann’s story; a real life ME battle

Me at my worst in 1993, with Mum and dogs and chicken!

M.E. and Me; Part 1: the dark days

By Ann Caird

The following post will be published in two parts; Part 1: The dark days and Part 2: Light at the end of the tunnel. Ann, a patient at Hadley wood Healthcare has generously supplied her real life story. It traces her persons battle with a debilitating illness and her eventual recovery and progression into a successful and for filling profession. Ann was keen to share her experiences with others in order to help support their fight and personal battles with similar health problems. ME, Chronic Fatigue Syndrome & Fibromyalgia present in so many ways and have so many treatment approaches; what helps one may not help another. What Ann’s story highlights is the fact that treatments can take different directions along the path to wellness and the sufferer has to take the rough with the smooth but perseverance and support wins through in the end!

1994. I had been lying in bed for nearly 2 years with an M.E. type illness. The doctors had done all the tests possible, which collectively indicated M.E.; there was nothing else that could be done for me within conventional medicine. Previously I had enjoyed a full active life and had travelled the world as a nanny and maternity nurse. Jim and I married in 1990, and I’d had shingles just before our wedding, from which I never really fully recovered. Over the previous 2 years, Jim had become my sole carer as my parents lived in Hertfordshire and we were in Perthshire, Scotland. Jim fed me, bathed me, shopped, cooked, as well as working full time on the family farm. He understood when I cried because I couldn’t speak to tell him what I needed or felt; the messages from my brain got confused and so at times it was too difficult for me to physically communicate my needs or emotions. I had immense pain when I ate, was losing weight rapidly, and weighed less than 7 stone. Something had to be done; help had to be found soon.

My parents attended a local M.E. group meeting where Jan de Vries gave a talk and there met Marcus Webb. They got an appointment with Marcus at the Hadley Wood clinic, described my symptoms and medical condition, and immediately my treatment started – we had a ray of hope! Marcus suspected a candida albicans infection in my gut, and his ‘blue loo’ test which he sent me confirmed his suspicions.

Marcus treated me ‘long distance’; the process of clearing my system of the candida was not pleasant, Marcus had warned me of this, but this was the only way to go now. I cut out all sugar, yeast, fruit and simple carbohydrates from my diet, and took medication to kill off the candida in my gut. As the candida died off, the Herxheimer Reaction kicked in, the spores released into my body caused undesirable side effects, but, this was evidence that the treatment was working. This was my lowest point, I felt like my body couldn’t take any more, I felt like I was dying, but I had to stick with it, it was the only way, and Marcus said it would get better… and of course, it did. Marcus then prescribed acidophilus pearls to reintroduce the good bacteria into my gut, and gently returned to a normal diet. I had no more stomach pain, I could eat freely now, so the recovery process could begin.

Once strong enough to travel, I stayed with my parents for a while so I could see Marcus weekly for treatment, and this is when the consequences of 2 years of enforced bed rest and poor digestion became evident. A bone density scan revealed the impact on my bones – I was at high risk of osteoporosis and my hips were on the osteoporosis fracture line on the charts. My muscles were weak and my spine bulged out as it had taken the shape of the bed I had been lying in, rather than having a strong ‘S’ shape. A displaced disc in my lower back caused immense pain when I walked more than 20 meters, so although I was on my feet, I was using a wheel chair much of the time. Marcus stressed the importance of a good, high quality diet, movement to whatever extent I could to start to reverse bone loss and work the muscles again and I started to take osteoprime and protein capsules. At this point I asked Marcus if I would ever be able to work again. The answer? Yes, if I did what I was told, worked at it and didn’t give up, there would be nothing stopping me doing whatever I wanted. So, a glimmer of hope for a normal life again, more than Jim and I had ever hoped for.

Back in Scotland again, and my hormones were in crisis. The mood swings were unbearable for both Jim and I, and I became very depressed as although the pain when walking was slowly improving, the improvement was very slow. Marcus suggested I take Femtrol to help me cope with extreme hormone fluctuations as my body tried to readjust to increasing weight gain and food, and fearing permanent nerve damage, arranged for me to have a cortisone epidural in the hope that the displaced disc would settle.

The results were miraculous! I could now walk without pain, no more wheel chairs! I could start gentle physical exercise to help strengthen muscle and bone and my moods swings began to even out a little. My recovery had taken huge positive step!

Continuing a good nutritional diet, osteoprime, femtrol and occasional digestive enzymes to support digestion, and walking regularly at last, I began to feel able to do something outside the home. I became a (very) part-time guide at Scone Palace, and how I loved it! The company of the other guides, talking to the visitors, giving talks to coach parties, what an improvement in my confidence! I coped by preparing and memorising an ‘informative talk’ for each section of the palace that I worked in, and it was clear that my ability to think and communicate had returned. However, when I get tired, I still occasionally struggle to speak, my brain goes into ‘shut down’, but it’s manageable and predictable now, and doesn’t affect my quality of life. My work at Scone demonstrated the increasing possibilities of a more ‘normal’ life for us.

My diet became critical to my ability to function and perform. I was eating 3 meals and 3 snacks daily, and if I didn’t eat regularly my blood sugar would plummet and I would shake with weakness. I now learned to have snacks concealed about my person in pockets and bags, wherever I was or whatever I was doing. To this day, I still can’t eat large meals; I continue to eat the 3 meals and 3 snacks every day.

Encouraged by my experiences at Scone, I updated my childcare knowledge at college, proving that I really could function in the outside world. In 1999, my updates complete, I started to work full-time within Early Years Education, a huge step, but weekends and holidays were critical resting periods for me. However, in 2001 niggling back problems returned. After an MRI scan Marcus referred me to Keiser Therapy for targeted strength training in London. The therapy was liberating – I was in the gym and my muscles were visibly building, huge progress once again. The niggling pains stopped, and I began to feel really strong again and cope more easily with everyday tasks.

Back in Scotland, I continued strength training myself. Using the Keiser Therapy as my foundation, I bought ankle and wrist weights, dumb bells, and resistance bands and began regular muscle and bone building exercise at home using the weights and combining them with Pilates exercises. Regular bone scans showed reversal of the previous bone density loss, and now I was building bone density steadily in both the hips and lower back.  I also now knew that my muscles had to be kept strong if I was to cope with everyday life. At this point, on Marcus’s suggestion, I began taking glucosamine, chondroitin, and MSM to support my back, bone and joint health.

Unfortunately another problem hit… I began experiencing deep pain in my right piriformis muscle when I walked, eventually being restricted to walking no more than 200 meters at a time (on a good day), and wearing just one pair of shoes. Trying to wear any other shoes resulted in immediate pain that lasted days. I became very depressed and fearful of losing everything I had worked for, including my job. Marcus advised as much physical therapy as possible – massage, craniosacral therapy, physiotherapy, reiki, orthotics – and I tried everything. My GP referred me to Cognitive Behavioural Therapy for emotional support and to help me overcome the practical issues of living with such pain. There were no more outdoor walks, walking in a classroom at work was bearable, I could cope with that, but that was my limit.

Part 2 to follow…

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Confirmation of viral link with ME/CFS

So many years on and we still do not have the cause of ME (myalgic encephalitis), also known as chronic fatigue syndrome (CFS) but as the research continues we may be getting a step closer. Recent findings have found a “strong link” with a retrovirus called XMRV.
Studies on 2009 found evidence of the xenotropic murine leukaemia virus-related virus (XMRV) in about two-thirds of the people with CFS and less than 4% of people without the disease. However, these findings alone do not prove that the virus causes CFS, because they do not show whether the infection occurred before or after CFS developed. The research paper is cautious in its conclusions, saying that XMRV “may” be a contributing factor to CFS, but the opposite may also be true: CFS may make people more susceptible to infection with this virus. The research lead by Dr Vincent Lombardi and entitled “Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome” published in the journal Science can be viewed here.
The research found that blood from 67% of people with CFS contained XMRV DNA compared with 3.7% of controls, overall samples from people with CFS were 54 times as likely to contain viral sequences as samples from healthy controls. This lead the researchers to conclude that XMRV may be a contributing factor in the development of CFS. They suggest that infection with the XMRV virus could be responsible for some of the abnormal immune response and neurological problems seen in CFS.
In a recent developement, a follow on study published in the Proceedings of the National Academy of Sciences (PNSA) showed that evidence of XMRV virus (and related viruses called “MLV”) was present in 86.5% of CFS patients vs. less than 7% of healthy controls. This is a dramatic difference and corroborates the previous findings. For details of the study click here.
To view more discussions relating to these new findings visit Dr Jacob Teitelbaum web site, click here. He has been following these developements with interest and has a wealth of resources on the subject. Click here.
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