Diindolylmethane (DIM); a potential breakthrough in the fight against ovarian cancer

Diindolylmethane (DIM) is a natural compound formed during the breakdown of a compound known as glucobrassicin present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale.

Scientists from Texas Tech University Health Sciences Center, Amarillo already knew that DIM inhibited the growth of ovarian cancer cells but have now found that DIM causes ovarian cancer cell death (apoptosis). Not only was DIM able to kill cells but it also prevented cell invasion and angiogenesis, both of which are necessary for a cancer to grow.

Prof Sanjay K. Srivastava and Prabodh K. Kandala who performed the research explained, “DIM increases the effect of cisplatin, without being toxic to normal ovarian cells, by targeting STAT3 signaling and increasing apoptosis. Cisplatin is very toxic and has severe side effects. If co-treatment with DIM means that a low dose of cisplatin can be given to patients without the loss of therapeutic effect, but with reduced side effects, it would represent a significant breakthrough in clinical practice.”

Further Reading on Diindolylmethane

Read the full story here: Diindolylmethane Suppresses Ovarian Cancer in Medical News Today

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