Researchers Find Possible Link Between Bacterium And Colon Cancer

A confirmed connection between Fusobacterium and the onset of colorectal cancer would mark the first time any microorganism has been found to play a role in this type of cancer, which is the second leading cause of cancer deaths in the United States. 

Follow the story here: Researchers Find Possible Link Between Bacterium And Colon Cancer.

The two independent teams found a potential association between colon cancer and a microorganism after they identified that Fusobacterium, a single genus of bacteria, was found more often in colon cancer tissue compared to normal tissue.

Follow this part of the story here: Fusobacterium Linked To Colorectal Cancer

Also of interest, Ginger root supplements may be worth investigating as a potential strategy for colon cancer prevention, according to a phase II study published in the 11 October issue of Cancer Prevention Research. Researchers from the University of Michigan Medical School and colleagues, found that ginger root supplement reduced levels of prostaglandin E2 (PGE2) and other biomarkers of colon inflammation in a select group of patients.

Follow the story here: Ginger Root Worth Investigating As Potential Colon Cancer Preventer

 

References:

”Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma.”
Castellarin M, Warren RL, Freeman D, Dreolini L, Krzywinski M, Strauss J, Barnes R, Watson P, Allen-Vercoe E, Moore RA, Holt RA.
Genome Research doi: 10.1101/gr.126516.111.

”Genomic analysis identifies association of Fusobacterium with colorectal carcinoma.”
Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, Ojesina AI, Jung J, Bass AJ, Tabernero J, Baselga J, Liu C, Shivdasani RA, Ogino S, Birren BW, Huttenhower C, Garrett WS, Meyerson M.
Genome Research doi: 10.1101/gr.126573.111.

“Phase II Study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer”; Suzanna M. Zick, D. Kim Turgeon, Shaiju K. Vareed, Mack T. Ruffin, Amie J. Litzinger, Benjamin D. Wright, Sara Alrawi, Daniel P. Normolle, Zora Djuric, and Dean E. Brenner;Cancer Prev Respublished online first 11 October 2011; DOI :10.1158/1940-6207.CAPR-11-0224

 

 

 

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